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Cytoplasmic Linker Associated Protein 1 Primary Antibody Unconjugated Public Immunogen Range 1-52/1538 Host Species Rabbit Target Species Human Mouse Rat Clonality Monoclonal Applications WB FCM IC Concentration Lot dependent Size 50 ul Storage Buffer Supplied in PBS (pH 7 4) containing 50% glycerol and 0 02% sodium azide
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Protease inhibitor cocktails are routinely employed in protein extraction protocols to limit protein degradation due to intrinsic cellular protease activity facilitating the preservation of native protein structure and biochemical properties Upon cell lysis or tissue homogenization endogenous proteases including cysteine proteases serine proteases acid proteases and aminopeptidases become activated and can degrade target proteins This ready-to-use cocktail formulation supplied in DMSO at a 100X concentration specifically inhibits proteases via a defined blend of inhibitors (AEBSF Aprotinin Bestatin E-64 Leupeptin and Pepstatin A) selected to broadly target proteolytic activity encountered in mammalian cell extracts or tissue lysates This EDTA-free protease inhibitor cocktail is particularly suitable for downstream applications sensitive to divalent cations protein phosphorylation analysis or enzyme assays
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Glutathione Synthetase Primary Antibody Unconjugated Public Immunogen Range 321-400/474 Host Species Rabbit Target Species Human Mouse Rat Clonality Monoclonal Applications WB FCM IC Concentration Lot dependent Size 50 ul Storage Buffer Supplied in PBS (pH 7 4) containing 50% glycerol and 0 02% sodium azide
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An ENPP1 inhibitor (IC50 = 0.26 µM in a cell-free assay); selective for ENPP1 over ENPP2-7 at 10 µM; decreases ENPP1 activity in MDA-MB-231 and C6 cancer cells at 10 µM
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CD46 was discovered in 1986 during a search for novel C3b-binding proteins CD46 is expressed ubiquitously and functions as a co-factor in the factor I-mediated proteolytic cleavage of C3b and C4b Its vital role in preventing complement deposition on host tissue is underpinned by the fact that deficiency of CD46 is a predisposing factor for numerous disease conditions arising from complement-mediated self-attack
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GITR (glucocorticoid-induced tumor necrosis factor receptor) also known as AITR and TNFRSF18 is a 40 kDa transmembrane glycoprotein that functions in immune regulation GIRT is a receptor for TNFSF18 Seems to be involved in interactions between activated T-lymphocytes and endothelial cells and in the regulation of T-cell receptor-mediated cell death Mediated NF-kappa-B activation via the TRAF2/NIK pathway
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